Abstract: Targeting strong ground pressure disasters induced by intense mining activities and hard-thick roof strata in the Inner Mongolia-Shaanxi mining area, this study proposes technical countermeasures for ground pressure control through underground regional fracturing in hard-thick roof strata. Integrated methodologies including theoretical analysis, physical modeling, and field trials were employed to investigate key fracturing technologies. The pressure relief mechanism of hydraulic fracturing for hard-thick roof strata, centered on strata structure control, was elucidated. A comprehensive technical workflow for regional fracturing was proposed, including: determination of the target fracturing horizon, design of the fracture network and optimization of key construction parameters, drilling of underground directional long boreholes, multi-stage fracturing within these boreholes, and monitoring and evaluation of the hydraulic fracturing effects. Moreover, an integrated technological system and associated equipment for underground regional fracturing of hard-thick roof strata in coal mines were developed and demonstrated for pressure relief in a super-large mining height panel. The results indicate that during the trial period, a total of 174 microseismic events related to roof breakage were recorded. Among these, 141 events (81.03% of the total) were of the 10² J energy level, with a total roof breakage energy of 7.39×10⁴ J. No major microseismic events with energy levels exceeding 10⁴ J occurred. The weighted average periodic weighting interval was 17.9 m, the average duration span of weightings was 10.7 m, the average leg closure was 375 mm, and the average dynamic load factor was 1.46. Field implementation demonstrates that regional hydraulic fracturing can promote the timely caving of hard-thick roof strata, reduce the periodic weighting interval, and effectively mitigate the intensity of ground pressure manifestations, thereby ensuring the safe and efficient extraction of the super-large mining height panel. The results validate the effectiveness and applicability of the regional fracturing countermeasure for controlling powerful ground pressure in thick-hard roof strata. This research can provide a valuable reference for preventing and controlling powerful ground pressure hazards associated with hard-thick roof strata in the Inner Mongolia-Shaanxi mining area.