Abstract: In order to ensure safety of mining 7^th Coalseam of a mine in Anhui Province,selecting a rational methane disaster comprehensive prevention mode is necessary. Mode of grid cross-strata borehole methane drainage in floor rock roadway is a main method for outburst area of single coalseam. This method had been used in test area of the first mining face,but the effect was not good. Therefore,this paper obtained analytical solution of methane flow differential equation by theoretical derivation and set up radial flow model of methane drainage by multi-physics field coupling software so as to optimize distance between cross-strata methane drainage boreholes. Results showed that for single borehole,if the effective drainage time was 3 months,methane drainage radius was 1. 5m; for intensive boreholes,if distance between boreholes was less than 5m,methane pressure might drop under limit value in 6 months and drainage effect was good.